Obesogens are why Diets aren’t working – Episode 18

Did you know that Obesogens are a main reason why we cannot lose weight, are stressed out and lowering our quality of life potential?

“Rise in Obesity Matches Rise in Chemical Use”

Source Endocrine Society

The Endocrine Society, the largest organization of experts devoted to research on hormones and the clinical practice of endocrinology, reports that “the rise in the incidence in obesity matches the rise in the use and distribution of industrial chemicals that may be playing a role in a generation of obesity, suggesting Endocrine Disrupting Chemicals (EDCs) may be linked to this epidemic” (Perrine, 2010). Endocrine disrupting chemicals (EDCs) are a type of obesogen that is broadly defined as chemicals that can interfere with hormone action. These EDCs play havoc in our bodies in many ways. For example, it is now clear that other hormone receptor types and functions, including those involved in metabolism, obesity and brain signaling can be targets of EDCs (The Endocrine Society, 2009). 

Obesogens

“Simply put, obesogens are chemicals that disrupt the function of our hormonal system, leading to weight gain and many of the diseases that curse the American populace. They enter our bodies from a variety of sources-from natural compounds found in soy products, from artificial hormones fed to our animals, from plastic pollutants in some food packaging, from chemicals added to processed foods, and from pesticides sprayed on our produce. They act in a variety of ways-mimicking human hormones such as estrogen, blocking the action of other hormones such as testosterone, and, in some cases, altering the functions of our genes and essentially programming us to gain weight” (Perrine, 2010).

Obesogens Hijack the Regulatory Systems Controlling Weight and Why Traditional Dieting Methods are Outdated

Frederick vom Saal, Ph.D., curators’ professor of biological science at the University of Missouri-Columbia has stated, “Obesogens are thought to act by hijacking the regulatory systems that control body weight” (vom Saal, F. et al, 2012).

This presence of obesogens is the first reason that traditional dieting methods have become outdated. Never before have traditional, low-carbohydrate, low-calorie diets been forced to accommodate for this level of synthetic chemicals and the adverse effects they have on the body. The body’s attempt to protect itself from the constant assault of synthetic toxins results in the production and storage fat.

Scientists have also found that low levels of certain compounds, such as bisphenol A – the building block of hard, polycarbonate plastic, including that in baby bottles – have surprising effects on cells growing in lab dishes. Usually, cells become fibroblasts that make up the body’s connective tissue. However, pre-fibroblasts have the potential to become adipocytes or fat cells. These studies show that bisphenol A and some other industrial compounds pushed pre-fibroblasts to become fat cells and stimulated the proliferation of existing fat cells.

Scientist Jerry Heindel believes this has enormous implications. He says, “The fact that an environmental chemical has the potential to stimulate growth of pre-adipocytes has enormous implications. If this happened in living animals as it did in cells in lab dishes, the result would be an animal [with] the tendency to become obese.”

Hendel’s studies also imply that a person’s toxic burden can have consequences for three to four generations after the time of exposure.

 “Researchers are reporting new data, both in animals and in humans, that indicate the effects of these chemicals can be seen not just in our bodies, but across three or four generations. So, a pregnant woman affects her children, grandchildren, and great grandchildren” (Perrine, 2010).

The US Centers for Disease Control and Prevention (CDC), through its National Centers for Health Statistics, has conducted a series of blood and urine tests on thousands of Americans, measuring and monitoring their absorption of chemical toxins, and at what concentrations these chemicals occur in the body. Think of it as an ongoing “Manhattan Project” of public health research.

Four reports have been produced so far: for the years 1999-2000, 2001-2002, 2003-2004, and 2010, with each report summarizing chemical exposure residues (a process called “biomonitoring”) as found in about 10,000 people altogether, representing all ages and ethnic backgrounds. These lab tests, which are sophisticated and expensive, provide data on extremely low levels of toxins found in the human body, down to the parts-per-million and parts-per-billion levels of molecule detection. 

Each report has expanded the numbers of chemicals that were searched for and ultimately detected in body fluids. In the first report, for instance, dozens of industrial chemicals were on the target list, with each subsequent report adding dozens more chemicals for analysis, until by the fourth report, 212 chemicals had been included. 14

Newly Discovered Scientific Evidence on Obesogens and Weight Gain

[a] A New Discovery about What Really Makes Us fat

If you think that gaining weight is just about eating too much, absorbing too many calories, and not getting enough exercise, think again! Scientists at the Department of Developmental and Cell Biology, University of California, Irvine, examined the health impact from a category of toxins called endocrine disrupting chemicals (EDCs), and how these toxins influence weight gain, while thwarting attempts to lose weight. It didn’t receive much publicity, or medical expert attention, as pioneering medical studies with startling findings go. But it certainly should have, given its profound implications for the future of human health.

“There is an urgent, unmet need to understand the mechanisms underlying how exposure to certain EDCs may predispose our population to be obese,” the scientists wrote for their study, published in 2016 by the American Journal of Obstetrics and Gynecology.

Though this connection between weight gain and EDC toxins—particularly a subset of EDCs called “obesogens”—had been theorized a few years earlier, the authors of this study took the research to a deeper and unprecedented level of understanding by asking how and why this connection happens. The term “obesogens,” referring to environmental chemical molecules that trigger weight gain, was first coined in 2006 by two university scientists writing in the journal Endocrinology.

Think of obesogens as metabolic disrupters in the human body, which are skilled at promoting the creation of excess body fat “by altering programming of fat cell development, increasing energy storage in fat tissue, and interfering with neuroendocrine control of appetite,” as the study research team explained.

While the dramatic increase in obesity among all age groups is alarming in itself, what alerted the scientists to a thornier problem was “the rise in obesity rates among children under two years of age . . . since it is improbable that children in this age group are consuming more food or exercising less than previous generations.”

What became clear to the scientists was that toxic chemical influences from mother to fetus, as the fetus developed in the womb, were programming the children to unnaturally develop excess fat deposits after being born. In other words, many children are being born to become fat, no matter how much they exercise or how healthy they eat.

Unfortunately, many of us contain a large number of these chemicals within our bodies, and they are creating a toxic atmosphere that is seriously damaging our health, partly because many of these toxins build up over time and interact with one another in harmful ways. They are in the air we breathe, water we drink, food we consume, and personal care products we apply. We are literally drowning in toxins. They are the super bug of this century, and they are ultimately destroying us. (TDOS Syndrome 2017)

Mount Sinai Medical School does Study on Toxins in Humans in 2005

The research on this generational battle is all without true regard for how the body is handling these high levels of poison. Major studies conducted by Mt. Sinai Medical School have shown that the body stores elements of pollution, acid and impurities in fat cells. In these studies, all participants tested positive for between 100 and 170 toxic chemicals in their blood and urine. None were free from some form of toxicity.

Considering all this information – the buildup of chemicals, pesticides and hormones in the body – it is heavily implied that a strong correlation exists between a person’s toxic burden and the size of his or her waistline. These impurities may not only be helping the body to store fat but they are changing the body’s genetic structures to self-regulate.

 Paula Bailey Hamilton M.D. “Our Slimming System is Being Poisoned by Toxic Chemicals Creating Difficulty to Control Weight”

Dr. Paula Baillie-Hamilton is a medical doctor and visiting fellow in occupational and environmental health at Stirling University in Scotland. She is also considered to be one of the world’s leading authorities on toxic chemicals and their effects on our health. She believes that, “What appears to be happening is that our natural slimming system is being poisoned by the toxic chemicals we encounter in our everyday lives and this damage is making it increasingly difficult for our bodies to control their weight. The end result is that we gain weight in the form of fat and not muscle as chemicals tend to cause muscles to shrink and body fat to accumulate” (Baillie-Hamilton, 2005).

The great news is that there are 5 peer reviewed studies that analyzed a revolutionary new protocol that removes toxins and as result people lose tremendous amounts of weight safely and greatly increase your quality of life potential.